The first case study was my own body.

I didn't come to this work through a textbook. I came through my own biology.

10 yrs
APPLIED PRACTICE
Bio age 42 → 29
Free T 280 → 840
Origin Story
Andrew Martin
ROLE Founder, Second Prime
DISCIPLINE Biology · Human Physiology
FOCUS Longevity · Performance · Root Cause
CLIENTS 1,000+ (500 founders & execs)
TENURE 10 years applied practice

A biologist who got sick, and rebuilt himself from data.

"I had all the textbook answers and none of the actual ones."

A decade ago I was a biologist with a background in human physiology, and I was sick. An autoimmune condition was quietly dismantling my health. Despite everything I knew professionally, I was exhausted, inflamed, and operating at a fraction of my capacity. Conventional medicine offered management. I wanted answers.

What followed was years of applying the same precision I'd used in research to my own biology. Test. Measure. Hypothesize. Adjust. Re-test. I rebuilt myself from the ground up, not through willpower, but through data, root cause clarity, and a system that actually matched the demands I was placing on my body.

Along the way I worked with over 1,000 clients. More than 500 of them founders, executives, and high-output operators. The same pattern showed up every time: disciplined, intelligent people putting in real effort and still not getting the results they deserved. Not because they were doing something wrong. Because no one had ever built a system around them.

My own deltas over 10 years
ANDREW'S OWN DELTAS 10-YEAR REBUILD
hs-CRP
12.4 0.4 mg/L
Chronic inflammation → resolved
Cortisol AM
28 14 μg/dL
HPA axis regulated
Free Testosterone
280 840 pg/mL
3× increase
Biological age
42 29 yrs
13-year reduction

Andrew Martin, Founder, Second Prime

Operating Principles

How the work actually gets done.

Every protocol at Second Prime traces back to these four rules. No exceptions.

01

Measure completely.

If you haven't measured it, you can't optimize it. Assumption is the enemy of progress.

02

Interpret for performance.

"Normal" is an average. Your biology is not average. Every result is read against the high end, not the middle.

03

Build one system.

Nutrition, training, supplementation, therapies, recovery. One integrated protocol. Nothing lost between providers.

04

Adjust from data.

Every protocol shift is traceable to a measurement. Your biology tells us what it needs. We listen.

Scale of Practice

Ten years. A thousand bodies. One system.

0 + clients
Served over 10 years
0 + execs
Founders, CEOs, partners
0 yrs
Andrew's own bio age reduction

Ready to have someone actually build a system around you?

A 30-minute conversation to determine fit. If Second Prime is the right move, we'll tell you. If it isn't, we'll point you somewhere else.

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